Electrical stimulation of cortex improves corticospinal tract tracing in rat spinal cord using manganese-enhanced

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dc.contributor.author Peng, Warner
dc.date.accessioned 2006-06-30T20:11:28Z
dc.date.available 2006-06-30T20:11:28Z
dc.date.issued 2006-06-30T20:11:28Z
dc.identifier.uri http://hdl.handle.net/2271/157
dc.description Neuroscience II Room 1028 Dykes 10:48 AM Abstract 150 en
dc.description.abstract Following bilateral injection of manganese (Mn) into the rat’s motor cortex, electrical stimulation of the cortex is shown to increase the transport, uptake and accumulation of Mn in the corticospinal tract (CST), as assessed by manganese-enhanced magnetic resonance imaging (MEI). T1-weighted gradient echo images were acquired in 3-D and displayed in different orientations to anatomically delineate the CST pathway from cortex to spinal cord (SC) at the thoracic level. T1-maps of the SC were produced from spin-echo based image data to demonstrate the distribution of the T1 properties of the SC tissue and to quantitatively assess the T1-change occurring in the CST due to the presence of Mn therein. Implications of improving the tract tracing ability with the proposed in vivo approach and its application to spinal cord injury (SCI) research are discussed in terms of aiding future experimental investigations of neuroplasticity following an injury. en
dc.description.sponsorship Cheney, Paul Molecular and Integrative Physiology en
dc.format.extent 1217536 bytes
dc.format.mimetype application/vnd.ms-powerpoint
dc.language.iso en_US en
dc.subject magnetic resonance imaging en
dc.subject spinal cord en
dc.subject corticospinal tract en
dc.subject manganese en
dc.subject manganese-enhanced MRI en
dc.subject Electrical stimulation en
dc.title Electrical stimulation of cortex improves corticospinal tract tracing in rat spinal cord using manganese-enhanced en
dc.type Presentation en

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