Browsing KU Med Libraries by Author "Pancewicz, Joanna"

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Current views on the role of Notch signaling and the pathogenesis of human leukemia

Pancewicz, Joanna; Nicot, Christophe (2011-11-30)

Abstract The Notch signaling pathway is highly conserved from Drosophila to humans and plays an important role in the regulation of cellular proliferation, differentiation and apoptosis. Constitutive activation of Notch ...
HTLV-I p30 inhibits multiple S phase entry checkpoints, decreases cyclin E-CDK2 interactions and delays cell cycle progression.

Baydoun, Hicham H; Pancewicz, Joanna; Bai, XueTao; Nicot, Christophe (2010-11-23)

Abstract Background Human T-cell leukemia virus type I (HTLV-I) has efficiently adapted to its host and establishes a persistent infection characterized by low levels of viral gene expression and slow proliferation of ...