Similarity searches in genome-wide numerical data sets

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dc.contributor.author Galina Glazko en_US
dc.contributor.author Michael Coleman en_US
dc.contributor.author Arcady Mushegian en_US
dc.date.accessioned 2009-05-05T16:15:57Z
dc.date.available 2006 - en_US
dc.date.available 2009-05-05T16:15:57Z
dc.date.issued 2008-07-25 en_US
dc.identifier.citation Galina Glazko;Michael Coleman;Arcady Mushegian: Similarity searches in genome-wide numerical data sets. Biology Direct 2006, 1(1):13. en_US
dc.identifier.uri http://www.biology-direct.com/content/1/1/13 en_US
dc.identifier.uri http://hdl.handle.net/2271/615
dc.description.abstract We present psi-square, a program for searching the space of gene vectors. The program starts with a gene vector, i.e., the set of measurements associated with a gene, and finds similar vectors, derives a probabilistic model of these vectors, then repeats search using this model as a query, and continues to update the model and search again, until convergence. When applied to three different pathway-discovery problems, psi-square was generally more sensitive and sometimes more specific than the ad hoc methods developed for solving each of these problems before.REVIEWERS:This article was reviewed by King Jordan, Mikhail Gelfand, Nicolas Galtier and Sarah Teichmann. en_US
dc.format.extent 666163 bytes
dc.format.extent 2910 bytes
dc.format.extent 12055 bytes
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dc.format.extent 43 bytes
dc.format.mimetype application/pdf
dc.format.mimetype text/plain
dc.format.mimetype application/octet-stream
dc.format.mimetype application/octet-stream
dc.format.mimetype application/octet-stream
dc.language en en_US
dc.language.iso en_US
dc.publisher BioMedCentral en_US
dc.relation.ispartof 1745-6150 en_US
dc.relation.hasversion http://www.biomedcentral.com/content/pdf/1745-6150-1-13.pdf en_US
dc.rights This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. en_US
dc.rights.uri http://creativecommons.org/licenses/by/2.0 en_US
dc.title Similarity searches in genome-wide numerical data sets en_US
dc.type article en_US
dc.date.captured 2009-04-27 en_US
dc.identifier.doi doi:10.1186/1745-6150-1-13 en_US
dc.identifier.pmid 18655715 en_US

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Except where otherwise noted, this item's license is described as This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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