Browsing BioMedCentral SWORD Deposits by Submit Date

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Browsing BioMedCentral SWORD Deposits by Submit Date

Now showing items 1-20 of 33

The environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin disrupts morphogenesis of the rat pre-implantation embryo

Hutt, Karla J; Shi, Zhanquan; Albertini, David F; Petroff, Brian K (2008-01-02)

Abstract Background Environmental toxicants, whose actions are often mediated through the aryl hydrocarbon receptor (AhR) pathway, pose risks to the health and well-being of exposed species, including humans. Of particular ...
Brain Research to Ameliorate Impaired Neurodevelopment: Home-based Intervention Trial (BRAIN-HIT)

Wallander, Jan L; McClure, Elizabeth; Biasini, Fred; Goudar, Shivaprasad; Pasha, Omrana; Chomba, Elwyn; Shearer, Darlene; Wright, Linda; Thorsten, Vanessa; Chakraborty, Hrishikesh; Dhaded, Sangappa M; Mahantshetti, Niranjana S; Bellad, Roopa M; Abbasi, Zahid; Carlo, Waldemar; [bhi], BRAIN-HIT Investigators (2010-04-30)

Abstract Background This randomized controlled trial aims to evaluate the effects of an early developmental intervention program on the development of young children in low- and low-middle-income countries who are at risk ...
Increase in isolation of extended spectrum beta lactamase producing multidrug resistant non typhoidal Salmonellae in Pakistan

Jabeen, Kauser; Zafar, Afia; Irfan, Seema; Khan, Erum; Mehraj, Vikram; Hasan, Rumina (2010-04-22)

Abstract Background Increasing resistance to quinolones and ceftriaxone in non typhoidal Salmonellae is a global concern. Resistance to quinolone and 3rd generation cephalosporin amongst non typhoidal Salmonellae (NTS) ...
The 3rdComputational Structural Bioinformatics Workshop

Unknown author (2010-05-17)
Protein structure determination via an efficient geometric build-up algorithm

Unknown author (2010-05-17)

Abstract Background A protein structure can be determined by solving a so-called distance geometry problem whenever a set of inter-atomic distances is available and sufficient. However, the problem is intractable in general ...
Intricacies in the surgical management of appendiceal mucinous cystadenoma: a case report and review of the literature

Khan, Muhammad R; Ahmed, Rashida; Saleem, Taimur (2010-05-05)

Abstract Introduction Mucinous cystadenoma is a type of mucocele of the appendix that is rarely encountered in clinical practice. Dogmatic consensus on the optimal surgical modus operandi of appendicular mucocele is lacking ...
Parent-child communication about sexual and reproductive health in rural Tanzania: Implications for young people's sexual health interventions

Wamoyi, Joyce; Fenwick, Angela; Urassa, Mark; Zaba, Basia; Stones, William (2010-05-12)

Abstract Background Many programmes on young people and HIV/AIDS prevention have focused on the in-school and channeled sexual and reproductive health messages through schools with limited activities for the young people's ...
Mathematical framework for human SLE Nephritis: disease dynamics and urine biomarkers

Budu-Grajdeanu, Paula; Schugart, Richard C; Friedman, Avner; Birmingham, Dan J; Rovin, Brad H (2010-05-17)

Abstract Background Although the prognosis for Lupus Nephritis (LN) has dramatically improved with aggressive immunosuppressive therapies, these drugs carry significant side effects. To improve the effectiveness of these ...
Immune function and health outcomes in women with depression

Howk, Cherie; Bennett, Mary (2010-05-03)

Abstract This research reports immune function and health outcomes in women with depression, as compared with a non-depressed control group. Using Psychoneuroimmunolgy theory and a descriptive comparison design, scores on ...
Noncutaneous malignant melanoma: a prognostic model from a retrospective multicenter study

Kim, Hyo Song; Kim, Eun Kyoung; Jun, Hyun Jung; Oh, Sung Yong; Park, Keon Woo; Lim, Do Hyeong; Lee, Soon Il; Kim, Jung-Han; Kim, Kyoung Mee; Lee, Dae Ho; Lee, Jeeyun (2010-04-28)

Abstract Background We performed multicenter study to define clinical characteristics of noncutaneous melanomas and to establish prognostic factors patients who received curative resection. Methods Of the 141 patients who ...
Severity of acute hepatitis and its outcome in patients with dengue fever in a tertiary care hospital Karachi, Pakistan (South Asia):

Parkash, Om; Almas, Aysha; Jafri, SM Wasim; Hamid, Saeed; Akhtar, Jaweed; Alishah, Hasnain (2010-05-07)

Abstract Background Liver injury due to dengue viral infection is not uncommon. Acute liver injury is a severe complicating factor in dengue, predisposing to life-threatening hemorrhage, Disseminated Intravascular Coagulation ...
A multicentre matched case control study of risk factors for Preeclampsia in healthy women in Pakistan

Shamsi, Uzma; Hatcher, Juanita; Shamsi, Azra; Zuberi, Nadeem; Qadri, Zeeshan; Saleem, Sarah (2010-04-30)

Abstract Background Preeclampsia is one of the leading causes of maternal and perinatal morbidity and mortality world-wide. The risk for developing preeclampsia varies depending on the underlying mechanism. Because the ...
A Markov blanket-based method for detecting causal SNPs in GWAS

Unknown author (2010-04-29)

Abstract Background Detecting epistatic interactions associated with complex and common diseases can help to improve prevention, diagnosis and treatment of these diseases. With the development of genome-wide association ...
Application of Kernel Functions for Accurate Similarity Search in Large Chemical Databases

Unknown author (2010-04-29)

Abstract Background Similaritysearch in chemical structure databases is an important problem with many applications in chemical genomics, drug design, and efficient chemical probe screening among others. It is widely ...
Comparison of a reduced carbohydrate and reduced fat diet for LDL, HDL, and VLDL subclasses during 9-months of weight maintenance subsequent to weight loss

LeCheminant, James D; Smith, Bryan K; Westman, Eric C; Vernon, Mary C; Donnelly, Joseph E (2010-06-01)

Abstract Objectives This study compared LDL, HDL, and VLDL subclasses in overweight or obese adults consuming either a reduced carbohydrate (RC) or reduced fat (RF) weight maintenance diet for 9 months following significant ...
The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition.

Tang, Su-Ni; Singh, Chandan; Nall, Dara; Meagher, Daniel; Shankar, Sharmila; Srivastava, Rakesh K (2010-08-18)

Abstract Background Much attention has been recently focused on the role of cancer stem cells (CSCs) in the initiation and progression of solid malignancies. Since CSCs are able to proliferate and self-renew extensively ...
Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate

Wang, Xinkun; Bao, Xiaodong; Pal, Ranu; Agbas, Abdulbaki; Michaelis, Elias K (2010-06-07)

Abstract Background Increases during aging in extracellular levels of glutamate (Glu), the major excitatory neurotransmitter in the brain, may be linked to chronic neurodegenerative diseases. Little is known about the ...
Phosphatidylinositol 3 kinase modulation of trophoblast cell differentiation

Kent, Lindsey N.; Konno, Toshihiro; Soares, Michael J. (2010-09-14)

Abstract Background The trophoblast lineage arises as the first differentiation event during embryogenesis. Trophoblast giant cells are one of several end-stage products of trophoblast cell differentiation in rodents. These ...
Lubiprostone ameliorates the cystic fibrosis mouse intestinal phenotype

De Lisle, Robert C; Mueller, Racquel; Roach, Eileen (2010-09-15)

Abstract Background Cystic fibrosis (CF) is caused by mutations in the CFTR gene that impair the function of CFTR, a cAMP-regulated anion channel. In the small intestine loss of CFTR function creates a dehydrated, acidic ...
The effect of starting point placement technique on thoracic transverse process strength: an ex vivo biomechanical study

Brown, Barrett S; McIff, Terence E; Glattes, Rudolph C; Burton, Douglas C; Asher, Marc A (2010-07-13)

Abstract Background The use of thoracic pedicle screws in spinal deformity, trauma, and tumor reconstruction is becoming more common. Unsuccessful screw placement may require salvage techniques utilizing transverse process ...