Browsing BioMedCentral SWORD Deposits by Page Number

Archie Digital Collections

Browsing BioMedCentral SWORD Deposits by Page Number

Now showing items 1-20 of 33

The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition.

Tang, Su-Ni; Singh, Chandan; Nall, Dara; Meagher, Daniel; Shankar, Sharmila; Srivastava, Rakesh K (2010-08-18)

Abstract Background Much attention has been recently focused on the role of cancer stem cells (CSCs) in the initiation and progression of solid malignancies. Since CSCs are able to proliferate and self-renew extensively ...
Phosphatidylinositol 3 kinase modulation of trophoblast cell differentiation

Kent, Lindsey N.; Konno, Toshihiro; Soares, Michael J. (2010-09-14)

Abstract Background The trophoblast lineage arises as the first differentiation event during embryogenesis. Trophoblast giant cells are one of several end-stage products of trophoblast cell differentiation in rodents. These ...
Immortalized, pre-malignant epithelial cell populations contain long-lived, label-retaining cells that asymmetrically divide and retain their template DNA

Bussard, Karen M; Boulanger, Corinne A; Kittrell, Frances S; Behbod, Fariba; Medina, Daniel; Smith, Gilbert H (2010-10-21)

Abstract Introduction During selective segregation of DNA, a cell asymmetrically divides and retains its template DNA. Asymmetric division yields daughter cells whose genome reflects that of the parents, simultaneously ...
Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate

Wang, Xinkun; Bao, Xiaodong; Pal, Ranu; Agbas, Abdulbaki; Michaelis, Elias K (2010-06-07)

Abstract Background Increases during aging in extracellular levels of glutamate (Glu), the major excitatory neurotransmitter in the brain, may be linked to chronic neurodegenerative diseases. Little is known about the ...
Lubiprostone ameliorates the cystic fibrosis mouse intestinal phenotype

De Lisle, Robert C; Mueller, Racquel; Roach, Eileen (2010-09-15)

Abstract Background Cystic fibrosis (CF) is caused by mutations in the CFTR gene that impair the function of CFTR, a cAMP-regulated anion channel. In the small intestine loss of CFTR function creates a dehydrated, acidic ...
Tobacco use amongst out of school youth in a Local Government Area in Nigeria.

Adebiyi, Akindele O; Faseru, Babalola; Sangowawa, Adesola O; Owoaje, Eme T (2010-10-18)

Abstract Introduction Out-of-school adolescents are often neglected when planning for tobacco prevention programmes whereas they are more vulnerable. Few studies exist in Nigeria about their pattern of tobacco use to serve ...
Mammalian oocytes are targets for prostaglandin E2 (PGE2) action

Duffy, Diane M; McGinnis, Lynda K; VandeVoort, Catherine A; Christenson, Lane K (2010-11-01)

Abstract Background The ovulatory gonadotropin surge increases synthesis of prostaglandin E2 (PGE2) by the periovulatory follicle. PGE2 actions on granulosa cells are essential for successful ovulation. The aim of the ...
Development and validation of a FACS-based lipoprotein localization screen in the Lyme disease spirochete Borrelia burgdorferi

Kumru, Ozan S; Schulze, Ryan J; Slusser, Joyce G; Zuckert, Wolfram R (2010-11-03)

Abstract Background In our previous studies on lipoprotein secretion in the Lyme disease spirochete Borrelia burgdorferi, we used monomeric red fluorescent protein 1 (mRFP1) fused to specifically mutated outer surface ...
Sex partnerships, health, and social risks of young men leaving jail: analyzing data from a randomized controlled trial

Ramaswamy, Megha; Freudenberg, Nicholas (2010-11-10)

Abstract Background Young men involved in the criminal justice system face disproportionately high rates of sexual risk behavior, drug, use, and violence. Little is known about how their involvement in sex partnerships ...
A multicentre matched case control study of risk factors for Preeclampsia in healthy women in Pakistan

Shamsi, Uzma; Hatcher, Juanita; Shamsi, Azra; Zuberi, Nadeem; Qadri, Zeeshan; Saleem, Sarah (2010-04-30)

Abstract Background Preeclampsia is one of the leading causes of maternal and perinatal morbidity and mortality world-wide. The risk for developing preeclampsia varies depending on the underlying mechanism. Because the ...
A Markov blanket-based method for detecting causal SNPs in GWAS

Unknown author (2010-04-29)

Abstract Background Detecting epistatic interactions associated with complex and common diseases can help to improve prevention, diagnosis and treatment of these diseases. With the development of genome-wide association ...
Application of Kernel Functions for Accurate Similarity Search in Large Chemical Databases

Unknown author (2010-04-29)

Abstract Background Similaritysearch in chemical structure databases is an important problem with many applications in chemical genomics, drug design, and efficient chemical probe screening among others. It is widely ...
Increase in isolation of extended spectrum beta lactamase producing multidrug resistant non typhoidal Salmonellae in Pakistan

Jabeen, Kauser; Zafar, Afia; Irfan, Seema; Khan, Erum; Mehraj, Vikram; Hasan, Rumina (2010-04-22)

Abstract Background Increasing resistance to quinolones and ceftriaxone in non typhoidal Salmonellae is a global concern. Resistance to quinolone and 3rd generation cephalosporin amongst non typhoidal Salmonellae (NTS) ...
The 3rdComputational Structural Bioinformatics Workshop

Unknown author (2010-05-17)
Protein structure determination via an efficient geometric build-up algorithm

Unknown author (2010-05-17)

Abstract Background A protein structure can be determined by solving a so-called distance geometry problem whenever a set of inter-atomic distances is available and sufficient. However, the problem is intractable in general ...
Intricacies in the surgical management of appendiceal mucinous cystadenoma: a case report and review of the literature

Khan, Muhammad R; Ahmed, Rashida; Saleem, Taimur (2010-05-05)

Abstract Introduction Mucinous cystadenoma is a type of mucocele of the appendix that is rarely encountered in clinical practice. Dogmatic consensus on the optimal surgical modus operandi of appendicular mucocele is lacking ...
A longitudinal study of tobacco use among American Indian and Alaska Native tribal college students

Faseru, Babalola; Daley, Christine M; Gajewski, Byron; Pacheco, Christina M; Choi, Won S (2010-10-18)

Abstract Background American Indians (AI) have the highest smoking rates of any ethnic group in the US (40.8%), followed most closely by African Americans (24.3%) and European Americans (23.6%). AI smokers also have more ...
An in vitro study comparing a peripherally inserted central catheter to a conventional central venous catheter: no difference in static and dynamic pressure transmission

Latham, Heath E; Dwyer, Timothy T; Gregg, Bethene L; Simpson, Steven Q (2010-10-12)

Abstract Background Early goal directed therapy improves survival in patients with septic shock. Central venous pressure (CVP) monitoring is essential to guide adequate resuscitation. Use of peripherally inserted central ...
The effect of starting point placement technique on thoracic transverse process strength: an ex vivo biomechanical study

Brown, Barrett S; McIff, Terence E; Glattes, Rudolph C; Burton, Douglas C; Asher, Marc A (2010-07-13)

Abstract Background The use of thoracic pedicle screws in spinal deformity, trauma, and tumor reconstruction is becoming more common. Unsuccessful screw placement may require salvage techniques utilizing transverse process ...
Brain Research to Ameliorate Impaired Neurodevelopment: Home-based Intervention Trial (BRAIN-HIT)

Wallander, Jan L; McClure, Elizabeth; Biasini, Fred; Goudar, Shivaprasad; Pasha, Omrana; Chomba, Elwyn; Shearer, Darlene; Wright, Linda; Thorsten, Vanessa; Chakraborty, Hrishikesh; Dhaded, Sangappa M; Mahantshetti, Niranjana S; Bellad, Roopa M; Abbasi, Zahid; Carlo, Waldemar; [bhi], BRAIN-HIT Investigators (2010-04-30)

Abstract Background This randomized controlled trial aims to evaluate the effects of an early developmental intervention program on the development of young children in low- and low-middle-income countries who are at risk ...