Kaori Nakamoto; Shuang Wang; Robert Jenison; Grace Guo; Curtis Klaassen; Yu-Jui Wan; Xiao-bo Zhong
(BioMedCentral, 2005-05-27)
BACKGROUND:Cholesterol 7-alpha-hydroxylase (CYP7A1) is the rate limiting enzyme for converting cholesterol into bile acids. Genetic variations in the CYP7A1 gene have been associated with metabolic disorders of cholesterol ...