Prostate Cancer is one of the most common malignancies in the US. Activation of androgen receptor (AR) has been shown to play a critical role in the initiation, maintenance and progression of prostate cancer. In an attempt ...

Background: High-risk human papilloma virus (HR-HPV) is a recognized cause of cervical carcinoma and its precursors. HPV testing is recommended to triage the follow up for women with atypical squamous cells of undetermined ...

Human T-cell lymphoma/leukemia virus (HTLV) is the etiological agent of adult T-cell lymphoma (ATL). Over10-20 million people are infected with HTLV, which is endemic in regions of Japan, the Caribbean, South America, ...

The vertebrate body plan is characterized by a segmented organization, which is clearly visible at the level of the vertebral column, its associated muscles and the peripheral nervous system. This basic organization is ...

The hypothesis of this project was that extended exposure to microgravity has a negative impact on the ability of the male mammalian species to reproduce. Previous research showed that simulated microgravity using hindlimb ...

Nerve injury resulting from trauma frequently leads to loss of function due to neuronal degeneration and cell death. The molecular mechanisms involved in neuronal cell death are poorly understood, but are thought to ...

Oleanolic acid (OA) is a triterpenoid compound, which is a natural ingredient in some Chinese herbal medicines used for the treatment of hepatitis. OA has previously been shown in our laboratory to diminish the hepatotoxicity ...

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by multiple fluid-filled cysts resulting from increased proliferation and alterations in the fluid transport properties of the renal epithelium. The ...

Introduction. Alpha activity during wakefulness is thought to represent perceptual disengagement and a state of relaxation. Patients with primary insomnia (PIs) have often been observed exhibiting less alpha activity ...

High throughput gene expression analysis before and after the LH surge has provided insight into the diversity of ovarian genes involved in oocyte maturation, ovulation, and luteinization. However, steady state gene ...